Micky van de Ven Brace Halts The Toffees' Run at New Home Ground
Micky van de Ven emerged as the first backline player to score twice in a English top-flight match for Spurs since the Belgian defender in spring 2013.
At a glance
The Spurs defender nods home two times in opening period
The home side's defender has equalizer ruled after VAR review
Senegalese midfielder scores third in 89th minute
This loss is Everton's first at Hill Dickinson Stadium
Micky van de Ven found the net on two occasions as Spurs extended their winning streak in away games in the Premier League and delivered Everton their initial loss at their new home.
Everton were unbeaten in their five previous fixtures at their new ground at the dockside location, having left Goodison Park behind after more than a century at the end of last season.
But Tottenham's leader the Dutchman struck on two occasions from set-pieces in the opening 45 minutes to put their impressive record at jeopardy, and they were failed to turn it around before Pape Matar Sarr - assisted by former Toffees attacker Richarlison - headed home a final goal to seal the victory.
Jake O'Brien believed he had levelled the scores a short while after Van de Ven's first goal, glancing a bullet header past the Spurs keeper from an set-piece.
Beto, in the meantime, failed to convert a handful of opportunities, while Vicario made a series of fine stops to ensure the London club went five matches on the road without defeat in the English top flight.
But the VAR stepped in, advising the match official to review the score on the pitchside monitor and the official ruled that Jack Grealish and the attacker were in offside positions and had interfered with the Tottenham goalkeeper.
This victory elevates Thomas Frank's team up to third in the division, a handful of points off north London rivals and leaders Arsenal.
The Merseyside club stay 14th and are six points ahead of the drop zone.
Tottenham analysis: Van de Ven fulfils duties at each end of pitch
After a uninspiring weekday display in the European competition against Monaco, where they managed a mere attempts on goal, the manager opted for Randal Kolo Muani in attack instead of former Toffees player the Brazilian.
The summer signing was failed to make much of an impact before being replaced for the substitute after 60 minutes on the field, but it emerged he proved unnecessary in the end.
Centre-back the Dutchman converted into an attacking force to be reckoned with.
Spurs' first goal came from a cleverly executed corner routine, with Rodrigo Bentancur heading the ball toward the six-yard box for an free Van de Ven to head home.
And Ven de Ven - filling in as skipper in the Argentine's absence - added his next goal in added time as he outjumped Jordan Pickford to head home.
The Dutchman was just as outstanding in defensive duties, partnering effectively with Kevin Danso as the duo dealt superbly with the 34 crosses sent their way by the opposition.
Everton analysis: Everton lacking finishing touch
Everton's recent stadium had been a fortress, but it appears the freshness may have worn off slightly and fans flocked to the exits after Sarr's third for Tottenham.
The break in the team's winning streak at home won't be a massive concern for David Moyes, but their striker situation are.
Beto and Thierno Barry - the Toffees' pair of established centre-forwards - had netted only one league goal combined before Sunday's outing.
And they were unable to contribute to that poor tally on a wet and gloomy evening on in Liverpool.
The striker's form was epitomized when he opted to bicycle-kick a clear chance from close range, despite having room and time to reposition for a more conventional shot that would have tested Vicario.
Barry, as well, was unable to influence the game after coming on for the starter in the second half.
It was not for a shortage of opportunity. The majority of the home side's offensive moves came through the winger and Ndiaye, who tirelessly delivered threatening crosses into the Tottenham penalty area.
Upcoming fixtures for these two sides?
The Toffees: Moyes' men travel to Sunderland in the Premier League on Monday, 3 November at 20:00 GMT.
Spurs: Spurs go to St James' Park on Wednesday, 29 October for their next round Carabao Cup match against Newcastle.